The key to combating infectious diseases is a detailed understanding of the underlying molecular mechanisms. The scientists at the CSSB investigate the structure, dynamics and function of pathogens in order to understand their host interactions. The CSSB's research is intended to enable the identification of targets for interventions. Three universities and six research institutions work together in the CSSB.
Research in the service of society
Malaria continues to be a major global health burden, causing around 450,000 deaths annually. In the CSSB lighthouse project "PLASMOFRACTION", scientists are investigating the sexual gametocyte stage of the parasite P. falciparum\-parasite.
The gametocyte is the only developmental stage in the parasite's complex life cycle that enables transmission to mosquitoes, making it a prime target for new interventions such as transmission-inhibiting drugs and vaccines.
This project combines the expertise of various CSSB groups and two Core Facilities. In the CSSB lighthouse project "PLASMOFRACTION", scientists are investigating the sexual gametocyte stage of the parasite P. falciparum. This stage is a target for new intervention measures such as drugs and vaccines.
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